Case Report

Abstract

Modifying lifestyle-related risk factors in mild cognitive impairment (MCI) patients may prevent or delay dementia progression. The SoUth Korean study to PrEvent cognitive impaiRment and protect BRAIN (SUPERBRAIN) health through lifestyle intervention in elderly people at risk is a part of the World-Wide FINGERS Network in South Korea. In this case, we conducted a SUPERBRAIN-based multidomain intervention in an MCI patient confirmed with Alzheimer’s pathology. After an 8-week intervention, the post-treatment total Repeatable Battery for the Assessment of Neuropsychological Status index score increased by 22 points, and the subdomain of memory, attention also improved. The SUPERBRAIN-based multi-domain intervention is an effective treatment on cognition even in amyloid positron emission tomography proven MCI patients.